ORC3 抗体 (N-Term)
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- 抗原 See all ORC3 抗体
- ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))
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抗原表位
- N-Term
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适用
- 人, 小鼠, Cow, 犬, 大鼠, Pig, 兔, 斑马鱼, Saccharomyces cerevisiae
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ORC3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RFETYQLIWQ QMKSENERLQ EELNKNLFDN LIEFLQKSHS GFQKNSRDLG
- 预测反应
- Cow: 93%, Dog: 93%, Human: 100%, Mouse: 79%, Pig: 90%, Rabbit: 93%, Rat: 83%, Yeast: 90%, Zebrafish: 85%
- 产品特性
- This is a rabbit polyclonal antibody against ORC3L. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product ORC3 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 712 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))
- 别名
- ORC3L (ORC3 产品)
- 背景
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The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Alias Symbols: LAT, LATHEO, ORC3, ORC3L
Protein Interaction Partner: ORC5, ORC4, ORC1, MCM7, CDC6, MCM10, ORC6, CCNE2, CDC45, LRWD1, ORC2, APP, SUMO2, XRCC5, UBC, XRCC6, ZBP1, DBF4, ORC3, MCM5, CDK4, TERF2, BRCA1, MCM4,
Protein Size: 712 - 分子量
- 82 kDa
- 基因ID
- 23595
- NCBI登录号
- NM_181837, NP_862820
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Feeding Behaviour, Synthesis of DNA
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