KIF7 抗体 (C-Term)
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Quick Overview for KIF7 抗体 (C-Term) (ABIN2788987)
抗原
See all KIF7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- RDLVHAPLPL TWKRSSLCGE EQGSPEELRQ REAAEPLVGR VLPVGEAGLP
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预测反应
- Cow: 92%, Dog: 79%, Human: 100%, Mouse: 77%, Pig: 100%, Rat: 77%
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产品特性
- This is a rabbit polyclonal antibody against KIF7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of human KIF7
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- KIF7 (Kinesin Family Member 7 (KIF7))
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别名
- KIF7
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背景
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This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.
Alias Symbols: ACLS, AGBK, HLS2, JBTS12, UNQ340
Protein Size: 829 -
分子量
- 91 kDa
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基因ID
- 374654
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NCBI登录号
- NM_198525, NP_940927
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UniProt
- Q2M1P5
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途径
- Hedgehog Signaling
抗原
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