HMGN3 抗体 (Middle Region)
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北京 101111
Quick Overview for HMGN3 抗体 (Middle Region) (ABIN2788959)
抗原
See all HMGN3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Hmgn3 Antibody - middle region
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序列
- SKPRKTSAKK EPGTKISRGA KGKKEEKQEA GEEGTAPSAN GDTKVEEAQR
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 100%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against Hmgn3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Mouse Hmgn3
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anti-High Mobility Group Nucleosomal Binding Domain 3 (HMGN3) (AA 1-30), (N-Term) antibody
HMGN3 适用: 人 WB 宿主: 兔 Polyclonal RB36390 unconjugated
anti-High Mobility Group Nucleosomal Binding Domain 3 (HMGN3) (AA 60-99) antibodyHMGN3 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosomal Binding Domain 3 (HMGN3) (C-Term) antibodyHMGN3 适用: 人, 小鼠, 大鼠, 马, 犬, 豚鼠, 兔, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosomal Binding Domain 3 (HMGN3) antibodyHMGN3 适用: 人, 小鼠, 大鼠 IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosomal Binding Domain 3 (HMGN3) (AA 1-77) antibodyHMGN3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosomal Binding Domain 3 (HMGN3) (AA 30-60) antibodyHMGN3 适用: 人 IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosomal Binding Domain 3 (HMGN3) (AA 41-90) antibodyHMGN3 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-High Mobility Group Nucleosomal Binding Domain 3 (HMGN3) (AA 1-30), (N-Term) antibodyHMGN3 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61954-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- HMGN3 (High Mobility Group Nucleosomal Binding Domain 3 (HMGN3))
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别名
- Hmgn3
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背景
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Background Information: Hmgn3 binds to nucleosomes, regulating chromatin structure and consequently, chromatin-dependent processes such as transcription, DNA replication and DNA repair. It affects both insulin and glucagon levels and modulates the expression of pancreatic genes involved in insulin secretion, regulates the expression of the glucose transporter SLC2A2 by binding specifically to its promoter region and recruiting PDX1 and additional transcription factors and regulates the expression of SLC6A9, a glycine transporter which regulates the glycine concentration in synaptic junctions in the central nervous system, by binding to its transcription start site. It may play a role in ocular development and astrocyte function.
Gene Name: high mobility group nucleosomal binding domain 3
Alternative Symbols: TR, HMGN, TRIP7, BB071015, 1110002A15Rik, 6330514M13Rik
Protein Name: High mobility group nucleosome-binding domain-containing protein 3
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分子量
- 11kDa
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基因ID
- 94353
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NCBI登录号
- NP_080398
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UniProt
- Q9DCB1
抗原
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