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BAG4 抗体 (C-Term)

BAG4 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788954
发货至: 中国
  • 抗原 See all BAG4 抗体
    BAG4 (BCL2-Associated Athanogene 4 (BAG4))
    抗原表位
    • 13
    • 8
    • 6
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 53
    • 16
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 兔, 斑马鱼
    宿主
    • 48
    • 4
    • 3
    • 1
    克隆类型
    • 55
    • 1
    多克隆
    标记
    • 29
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This BAG4 antibody is un-conjugated
    应用范围
    • 38
    • 24
    • 10
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB)
    序列
    EVEEFVGKKT DKAYWLLEEM LTKELLELDS VETGGQDSVR QARKEAVCKI
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
    产品特性
    This is a rabbit polyclonal antibody against BAG4. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product BAG4 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 457 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    BAG4 (BCL2-Associated Athanogene 4 (BAG4))
    别名
    BAG4 (BAG4 产品)
    别名
    BAG-4 antibody, SODD antibody, BAG4 antibody, fd20a04 antibody, wu:fd20a04 antibody, si:dkey-220o5.3 antibody, 2410112I15Rik antibody, ATBAG4 antibody, BCL-2-associated athanogene 4 antibody, BCL2 associated athanogene 4 antibody, BCL2-associated athanogene 4 antibody, BCL-2-associated athanogene 4 antibody, BAG4 antibody, Bag4 antibody, bag4 antibody
    背景
    The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
    Alias Symbols: BAG-4, SODD
    Protein Interaction Partner: EDC3, DCP1A, DNAJB12, DNAJC9, CD93, STUB1, DNAJB6, MLF2, DNAJC7, DNAJB1, HSPA8, HSPA2, HSPA1L, HSPA1B, DDX6, DCP1B, MCL1, CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A, CUL5, NEDD8, ELAVL1, UBC, TNFRSF25, APOBEC1, TNFRSF1A, BCL2, HSPA1A, HSP90AA1, HSPA4,
    Protein Size: 457
    分子量
    50 kDa
    基因ID
    9530
    NCBI登录号
    NM_004874, NP_004865
    UniProt
    O95429
    途径
    Regulation of Actin Filament Polymerization
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