BAG4 抗体 (C-Term)
Quick Overview for BAG4 抗体 (C-Term) (ABIN2788954)
抗原
See all BAG4 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- EVEEFVGKKT DKAYWLLEEM LTKELLELDS VETGGQDSVR QARKEAVCKI
-
预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%
-
产品特性
- This is a rabbit polyclonal antibody against BAG4. It was validated on Western Blot.
-
纯化方法
- Affinity Purified
-
-
anti-BCL2-Associated Athanogene 4 (BAG4) (AA 6-185) antibody
BAG4 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (AA 1-457) antibodyBAG4 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (AA 1-457) antibodyBAG4 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (C-Term) antibodyBAG4 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (Internal Region) antibodyVerified BAG4 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (C-Term) antibodyBAG4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (AA 1-457) antibodyBAG4 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (C-Term) antibodyBAG4 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (AA 443-457) antibodyBAG4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 4 (BAG4) (AA 226-275) antibodyBAG4 适用: 人, 犬, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 457 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- BAG4 (BCL2-Associated Athanogene 4 (BAG4))
-
别名
- BAG4
-
背景
-
The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 (TNF-R1) and death receptor-3 (DR3), and thereby negatively regulates downstream cell death signaling. The regulatory role of this protein in cell death was demonstrated in epithelial cells which undergo apoptosis while integrin mediated matrix contacts are lost. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Alias Symbols: BAG-4, SODD
Protein Interaction Partner: EDC3, DCP1A, DNAJB12, DNAJC9, CD93, STUB1, DNAJB6, MLF2, DNAJC7, DNAJB1, HSPA8, HSPA2, HSPA1L, HSPA1B, DDX6, DCP1B, MCL1, CAND1, DCUN1D1, COPS5, CUL1, CUL2, CUL3, CUL4A, CUL5, NEDD8, ELAVL1, UBC, TNFRSF25, APOBEC1, TNFRSF1A, BCL2, HSPA1A, HSP90AA1, HSPA4,
Protein Size: 457 -
分子量
- 50 kDa
-
基因ID
- 9530
-
NCBI登录号
- NM_004874, NP_004865
-
UniProt
- O95429
-
途径
- Regulation of Actin Filament Polymerization
抗原
-
