PDGFC 抗体 (N-Term)
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Quick Overview for PDGFC 抗体 (N-Term) (ABIN2788903)
抗原
See all PDGFC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MLLLGLLLLT SALAGQRTGT RAESNLSSKL QLSSDKEQNG VQDPRHERVV
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预测反应
- Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against Pdgfc. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Pdgfc
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PDGFC (Platelet-Derived Growth Factor C (PDGFC))
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别名
- Pdgfc
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背景
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Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.
Alias Symbols: 1110064L01Rik, AI647969, PDGF-C
Protein Size: 345 -
分子量
- 39 kDa
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基因ID
- 54635
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NCBI登录号
- NM_019971, NP_064355
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UniProt
- Q8CI19
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途径
- RTK signaling, Platelet-derived growth Factor Receptor Signaling
抗原
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