SCARB2 抗体 (N-Term)
Quick Overview for SCARB2 抗体 (N-Term) (ABIN2788867)
抗原
See all SCARB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VARVFQKAVD QSIEKKIVLR NGTEAFDSWE KPPLPVYTQF YFFNVTNPEE
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预测反应
- Cow: 86%, Dog: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against SCARB2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 478 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))
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别名
- SCARB2
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背景
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The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF).
Alias Symbols: AMRF, CD36L2, HLGP85, LIMPII, SR-BII, EPM4, LGP85, LIMP-2
Protein Interaction Partner: UBC, ATP4A, TAF15, NONO, HSPD1, DDX1, ATP6V1B1, Ap1g1, AP3S2, AP3S1, THBS1,
Protein Size: 478 -
分子量
- 53 kDa
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基因ID
- 950
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NCBI登录号
- NM_005506, NP_005497
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UniProt
- Q14108
抗原
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