GCK 抗体 (N-Term)
(1 reference)-
- 抗原 See all GCK 抗体
- GCK (Glucokinase (Hexokinase 4) (GCK))
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抗原表位
- N-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 绵羊, 兔, 豚鼠, 犬, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GCK antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RVMLVKVGEG EEGQWSVKTK HQMYSIPEDA MTGTAEMLFD YISECISDFL
- 预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 93%
- 产品特性
- This is a rabbit polyclonal antibody against GCK. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product GCK Primary Antibody
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anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibody
GCK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) antibodyGCK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 101-200) antibodyGCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 3-226) antibodyGCK 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-300) antibodyGCK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) antibodyGCK 适用: 人, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) antibodyGCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibodyGCK 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (AA 1-465) antibodyGCK 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Glucokinase (Hexokinase 4) (GCK) (C-Term) antibodyGCK 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 464 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Anti-diabetes effect of chronic intermittent hypobaric hypoxia through improving liver insulin resistance in diabetic rats." in: Life sciences, Vol. 150, pp. 1-7, (2016) (PubMed).
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: "Anti-diabetes effect of chronic intermittent hypobaric hypoxia through improving liver insulin resistance in diabetic rats." in: Life sciences, Vol. 150, pp. 1-7, (2016) (PubMed).
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- 抗原
- GCK (Glucokinase (Hexokinase 4) (GCK))
- 别名
- GCK (GCK 产品)
- 别名
- FGQTL3 antibody, GK antibody, GLK antibody, HHF3 antibody, HK4 antibody, HKIV antibody, HXKP antibody, LGLK antibody, MODY2 antibody, Gk antibody, Gls006 antibody, GCK antibody, BA4487 antibody, glk antibody, hk4 antibody, hhf3 antibody, hkiv antibody, hxkp antibody, gck-A antibody, mody2 antibody, glucokinase antibody, GLUKA antibody, RNGK2 antibody, glucokinase antibody, glucokinase (hexokinase 4) L homeolog antibody, glucokinase (hexokinase 4) antibody, GCK antibody, Gck antibody, glcK antibody, Bphyt_1025 antibody, Halhy_6548 antibody, gk antibody, gck.L antibody, gck antibody
- 背景
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).
Alias Symbols: FGQTL3, GK, GLK, HHF3, HK4, HKIV, HXKP, MODY2, LGLK
Protein Interaction Partner: PCNA, GCKR, INS, PFKFB2, MIG1,
Protein Size: 464 - 分子量
- 51 kDa
- 基因ID
- 2645
- NCBI登录号
- NM_033508, NP_277043
- 途径
- MAPK Pathway, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process
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