H2AFZ 抗体 (N-Term)
Quick Overview for H2AFZ 抗体 (N-Term) (ABIN2788776)
抗原
See all H2AFZ 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- AGGKAGKDSG KAKTKAVSRS QRAGLQFPVG RIHRHLKSRT TSHGRVGATA
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against H2AFZ. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 128 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
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别名
- H2AFZ
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背景
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Alias Symbols: H2A.z, H2A/z, H2AZ, MGC117173
Protein Interaction Partner: UBC, ASB9, ASB16, WWOX, ZBTB1, OGFOD1, TRNT1, ACAA2, NOL3, EZR, PYGL, PSMD9, FH, UBD, PAN2, HIST1H3B, CENPA, MAGEC1, SUMO1, SUMO3, NEDD8, EPC1, MEAF6, ACTR6, EP400, DMAP1, MRGBP, ING3, MORF4L1, RUVBL2, SRCAP, KAT5, RUVBL1, TRRAP, YEATS4, VPS72, ACTL6A, HI
Protein Size: 128 -
分子量
- 14 kDa
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基因ID
- 3015
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NCBI登录号
- NM_002106, NP_002097
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UniProt
- P0C0S5
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途径
- Telomere Maintenance
抗原
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