OGG1 抗体 (C-Term)
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北京 101111
Quick Overview for OGG1 抗体 (C-Term) (ABIN2788728)
抗原
See all OGG1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- OGG1 Antibody - C-terminal region
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序列
- AVPVDVHMWH IAQRDYSWHP TTSQAKGPSP QTNKELGNFF RSLWGPYAGW
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特异性
- Directed against isoforms 2D, 1A, 1B, 2E.
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预测反应
- Cow: 93%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 92%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against OGG1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-100), (N-Term) antibody
OGG1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IP, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 31-345) antibodyOGG1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 151-250) antibodyOGG1 适用: 人 WB, FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) antibodyOGG1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-345) antibodyOGG1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-324) antibodyOGG1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 1-324) antibodyOGG1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (Internal Region) antibodyVerified OGG1 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) antibodyOGG1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal CPTC-OGG1-1 unconjugated
anti-8-Oxoguanine DNA Glycosylase (OGG1) (AA 318-345), (C-Term) antibodyOGG1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB21522 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61228-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))
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别名
- OGG1
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背景
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Background Information: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization.
Gene Name: 8-oxoguanine DNA glycosylase
Alternative Symbols: HMMH, MUTM, OGH1, HOGG1
Protein Name: N-glycosylase/DNA lyase
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分子量
- 38kDa
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基因ID
- 4968
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NCBI登录号
- NP_058438
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UniProt
- O15527
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途径
- DNA Damage Repair
抗原
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