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OGG1 抗体 (C-Term)

This anti-OGG1 antibody is a 兔 多克隆 antibody detecting OGG1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, 马, Cow 和 Pig.
产品编号 ABIN2788728
发货至: 中国

Quick Overview for OGG1 抗体 (C-Term) (ABIN2788728)

抗原

See all OGG1 抗体
OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

适用

人, 小鼠, 大鼠, 犬, 马, Cow, Pig

宿主

  • 58
  • 16
  • 1

克隆类型

  • 53
  • 22
多克隆

标记

  • 33
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This OGG1 antibody is un-conjugated

应用范围

  • 44
  • 30
  • 15
  • 14
  • 11
  • 10
  • 8
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 16
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    AVPVDVHMWH IAQRDYSWHP TTSQAKGPSP QTNKELGNFF RSLWGPYAGW

    特异性

    Directed against isoforms 2D, 1A, 1B, 2E.

    预测反应

    Cow: 93%, Dog: 100%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 92%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against OGG1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 345 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

    别名

    OGG1

    背景

    This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization.
    Alias Symbols: HMMH, HOGG1, MUTM, OGH1
    Protein Interaction Partner: ERCC6, ERCC8, UBC, Ogg1, CHGB, XRCC1, PRKCA, SNRPF,
    Protein Size: 345

    分子量

    38 kDa

    基因ID

    4968

    NCBI登录号

    NM_016829, NP_058438

    UniProt

    O15527

    途径

    DNA Damage Repair
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