IRAK2 抗体 (C-Term)
Quick Overview for IRAK2 抗体 (C-Term) (ABIN2788725)
抗原
See all IRAK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SSSEACVGLE PPQDVTETSW QIEINEAKRK LMENILLYKE EKVDSIELFG
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预测反应
- Cow: 93%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Yeast: 83%
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产品特性
- This is a rabbit polyclonal antibody against IRAK2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human IRAK2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 625 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IRAK2 (Interleukin-1 Receptor-Associated Kinase 2 (IRAK2))
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别名
- IRAK2
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背景
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IRAK2 encodes the interleukin-1 receptor-associated kinase 2, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. IRAK2 is reported to participate in the IL1-induced upregulation of NF-kappaB.
Alias Symbols: IRAK-2, MGC150550
Protein Interaction Partner: TNFSF9, TRAF6, HSP90AA1, PSEN1, IRAK1, IL1R1, MYD88, UBC, TIRAP, SESTD1, ZC3H12C, ZC3H12A, FASTKD5, ADCK3, YTHDF1, TOLLIP, IRAK4, TARDBP, SARM1, SNRNP200, IRAK3, CDC37, IQSEC1, IQCB1, BAG3, STT3A, ARAF, TNFAIP3, MME, TICAM2, SMURF1, IRAK2, TLR4, SMAD2, HR
Protein Size: 625 -
分子量
- 69 kDa
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基因ID
- 3656
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NCBI登录号
- NM_001570, NP_001561
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UniProt
- O43187
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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