XPA 抗体 (C-Term)
Quick Overview for XPA 抗体 (C-Term) (ABIN2788719)
抗原
See all XPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- MKQKKFDKKV KELRRAVRSS VWKRETIVHQ HEYGPEENLE DDMYRKTCTM
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预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against XPA. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 273 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))
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别名
- XPA
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背景
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This gene encodes a zinc finger protein involved in DNA excision repair. The encoded protein is part of the NER (nucleotide excision repair) complext which is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens. Mutations in this gene are associated with xeroderma pigmentosum complementation group A. Alternatively spliced transcript variants have been found for this gene.
Alias Symbols: XP1, XPAC
Protein Interaction Partner: NDEL1, TRIM27, HERC2, ATR, PRKDC, ATM, HMGB1, ERCC1, DDB2, DDB1, RPA1, XPC, POLR2A, HHV8GK18_gp81, GTF2H1, ERCC6, RPA2, MSH3, MSH2, XAB2, GPN1, RPA4, RASSF1, GTF2E2, EP300,
Protein Size: 273 -
分子量
- 31 kDa
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基因ID
- 7507
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NCBI登录号
- NM_000380, NP_000371
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UniProt
- P23025
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途径
- DNA Damage Repair
抗原
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