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IL2 Receptor beta 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects IL2 Receptor beta in WB. It exhibits reactivity toward 人, 大鼠 和 Saccharomyces cerevisiae.
产品编号 ABIN2788713
发货至: 中国
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Quick Overview for IL2 Receptor beta 抗体 (C-Term) (ABIN2788713)

抗原

See all IL2 Receptor beta (IL2RB) 抗体
IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

适用

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人, 大鼠, Saccharomyces cerevisiae

宿主

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克隆类型

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  • 2
多克隆

标记

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This IL2 Receptor beta antibody is un-conjugated

应用范围

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  • 8
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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    QGYFFFHLPD ALEIEACQVY FTYDPYSEED PDEGVAGAPT GSSPQPLQPL

    预测反应

    Human: 100%, Rat: 77%, Yeast: 100%

    产品特性

    This is a rabbit polyclonal antibody against IL2RB. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 551 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

    别名

    IL2RB

    背景

    The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
    Alias Symbols: CD122, P70-75, IL15RB
    Protein Interaction Partner: ECM1, JAK1, SOCS3, LCK, NEDD4, HGS, UBC, EIF3B, STAT5B, SOCS1, CISH, STAT5A, IL15RA, SHC1, STAT1, IL15, SHB, JAK3, SYK, IL2RG, GNB2L1, PTPN6, PIK3R1, LYN, RAF1, IL2RA, IL2, FYN, GRB2, STAT3, JAK2,
    Protein Size: 551

    分子量

    58 kDa

    基因ID

    3560

    NCBI登录号

    NM_000878, NP_000869

    UniProt

    P14784

    途径

    JAK/STAT Signaling, Growth Factor Binding
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