IL2 Receptor beta 抗体 (C-Term)
Quick Overview for IL2 Receptor beta 抗体 (C-Term) (ABIN2788713)
抗原
See all IL2 Receptor beta (IL2RB) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- QGYFFFHLPD ALEIEACQVY FTYDPYSEED PDEGVAGAPT GSSPQPLQPL
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预测反应
- Human: 100%, Rat: 77%, Yeast: 100%
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产品特性
- This is a rabbit polyclonal antibody against IL2RB. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 551 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))
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别名
- IL2RB
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背景
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The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by this gene represents the beta subunit and is a type I membrane protein.
Alias Symbols: CD122, P70-75, IL15RB
Protein Interaction Partner: ECM1, JAK1, SOCS3, LCK, NEDD4, HGS, UBC, EIF3B, STAT5B, SOCS1, CISH, STAT5A, IL15RA, SHC1, STAT1, IL15, SHB, JAK3, SYK, IL2RG, GNB2L1, PTPN6, PIK3R1, LYN, RAF1, IL2RA, IL2, FYN, GRB2, STAT3, JAK2,
Protein Size: 551 -
分子量
- 58 kDa
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基因ID
- 3560
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NCBI登录号
- NM_000878, NP_000869
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UniProt
- P14784
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途径
- JAK/STAT Signaling, Growth Factor Binding
抗原
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