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PFKM 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects PFKM in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, 斑马鱼 和 Cow.
产品编号 ABIN2788704
发货至: 中国
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Quick Overview for PFKM 抗体 (C-Term) (ABIN2788704)

抗原

See all PFKM 抗体
PFKM (phosphofructokinase, Muscle (PFKM))

适用

  • 91
  • 49
  • 45
  • 8
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 兔, 犬, 豚鼠, 马, 斑马鱼, Cow

宿主

  • 83
  • 9
  • 6
  • 4

克隆类型

  • 65
  • 37
多克隆

标记

  • 52
  • 10
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
This PFKM antibody is un-conjugated

应用范围

  • 83
  • 37
  • 35
  • 34
  • 16
  • 13
  • 9
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 8
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    序列

    RALVFQPVAE LKDQTDFEHR IPKEQWWLKL RPILKILAKY EIDLDTSDHA

    预测反应

    Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%, Zebrafish: 86%

    产品特性

    This is a rabbit polyclonal antibody against PFKM. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PFKM
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 780 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PFKM (phosphofructokinase, Muscle (PFKM))

    别名

    PFKM

    背景

    Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
    Alias Symbols: GSD7, MGC8699, PFK-1, PFK1, PFKA, PFKX
    Protein Interaction Partner: UBC, SIAH1, PFKM, SUMO2, EGFR, DCP2, DCP1A, TUBB2A, PFKP, PCBP1, UBTD1, FBXO6, LSM7, PFKL, NDUFB2, Hoxa1, CUL3, MAPK3, PCNA, SUMO1, ATP6V0A4, FHL2, DYNLL1, CAV3, NOS1, HGS,
    Protein Size: 780

    分子量

    85 kDa

    基因ID

    5213

    NCBI登录号

    NM_000289, NP_000280

    UniProt

    P08237

    途径

    Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect
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