NQO1 抗体 (C-Term)
Quick Overview for NQO1 抗体 (C-Term) (ABIN2788701)
抗原
See all NQO1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- WKKRLENIWD ETPLYFAPSS LFDLNFQAGF LMKKEVQDEE KNKKFGLSVG
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预测反应
- Cow: 86%, Dog: 79%, Human: 100%, Rabbit: 91%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against NQO1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NQO1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 274 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))
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别名
- NQO1
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背景
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This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: DHQU, DIA4, DTD, NMOR1, NMORI, QR1
Protein Interaction Partner: UBC, FOS, NEDD8, SUMO1, NFE2L2, PARP1, BAG3, ITGA4, FN1, RPS10P5, POLDIP3, YTHDF1, RPS19, LAMB1, TP53, STUB1, ING1, DNAJB1, HSPA1A, NQO1, HSPA4,
Protein Size: 274 -
分子量
- 31 kDa
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基因ID
- 1728
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NCBI登录号
- NM_000903, NP_000894
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UniProt
- P15559
抗原
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