Hexokinase 1 抗体 (N-Term)
Quick Overview for Hexokinase 1 抗体 (N-Term) (ABIN2788663)
抗原
See all Hexokinase 1 (HK1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- CQQSKIDEAI LITWTKRFKA SGVEGADVVK LLNKAIKKRG DYDANIVAVV
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%
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产品特性
- This is a rabbit polyclonal antibody against HK1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human HK1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 921 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Hexokinase 1 (HK1)
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别名
- HK1
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背景
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Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Alias Symbols: HK1-ta, HK1-tb, HK1-tc, HKI, HXK1
Protein Interaction Partner: SUMO2, SUMO3, STAU1, UBC, EGFR, SUMO1, NEDD8, MDM2, WDR61, UBA5, PARP6, NSFL1C, ARFGAP1, UBXN1, TWF2, FKBP9, PDCD10, PROSC, PLAA, GTF3C4, TUFM, TUBB2A, SGTA, RARS, PCNA, HEXB, HEXA, CAPN2, ASL, AHCY, PARK2, ATF2, VDAC1, LIG4, APP, AKT1, CDK2, SIRT7, ICT1,
Protein Size: 921 -
分子量
- 103 kDa
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基因ID
- 3098
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NCBI登录号
- NM_033498, NP_277033
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UniProt
- P19367
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途径
- Carbohydrate Homeostasis, Warburg Effect
抗原
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