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Hexokinase 1 抗体 (Middle Region)

This anti-Hexokinase 1 antibody is a 兔 多克隆 antibody detecting Hexokinase 1 in WB. Suitable for 人, 小鼠, 大鼠, 犬, Cow, Pig, 兔, 马 和 豚鼠.
产品编号 ABIN2788662
发货至: 中国

Quick Overview for Hexokinase 1 抗体 (Middle Region) (ABIN2788662)

抗原

See all Hexokinase 1 (HK1) 抗体
Hexokinase 1 (HK1)

适用

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人, 小鼠, 大鼠, 犬, Cow, Pig, 兔, 马, 豚鼠

宿主

  • 116
  • 17

克隆类型

  • 107
  • 26
多克隆

标记

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This Hexokinase 1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 9
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    Middle Region

    序列

    ILVKMAKEGL LFEGRITPEL LTRGKFNTSD VSAIEKNKEG LHNAKEILTR

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 77%, Pig: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against HK1. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human HK1
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 921 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Hexokinase 1 (HK1)

    别名

    HK1

    背景

    Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus, the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
    Alias Symbols: HK1-ta, HK1-tb, HK1-tc, HKI, HXK1
    Protein Interaction Partner: SUMO2, SUMO3, STAU1, UBC, EGFR, SUMO1, NEDD8, MDM2, WDR61, UBA5, PARP6, NSFL1C, ARFGAP1, UBXN1, TWF2, FKBP9, PDCD10, PROSC, PLAA, GTF3C4, TUFM, TUBB2A, SGTA, RARS, PCNA, HEXB, HEXA, CAPN2, ASL, AHCY, PARK2, ATF2, VDAC1, LIG4, APP, AKT1, CDK2, SIRT7, ICT1,
    Protein Size: 921

    分子量

    103 kDa

    基因ID

    3098

    NCBI登录号

    NM_033498, NP_277033

    UniProt

    P19367

    途径

    Carbohydrate Homeostasis, Warburg Effect
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