Topoisomerase I 抗体 (N-Term)
-
- 抗原 See all Topoisomerase I (TOP1) 抗体
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
-
抗原表位
- N-Term
-
适用
- 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This Topoisomerase I antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 序列
- SNSEHKDSEK KHKEKEKTKH KDGSSEKHKD KHKDRDKEKR KEEKVRASGD
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against TOP1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- Top Product
- Discover our top product TOP1 Primary Antibody
-
-
- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
-
Antigen size: 765 AA
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- 抗原
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
- 别名
- TOP1 (TOP1 产品)
- 物质类
- Viral Protein
- 背景
-
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
Alias Symbols: TOPI
Protein Interaction Partner: SUMO2, SUMO3, MDM2, UBC, SUMO1, ERG, RNF2, EED, SHFM1, CDK14, TARDBP, CDK2, HDAC9, EIF2AK2, PARP1, WHSC1, VCAM1, ITGA4, IL7R, VCP, PA2G4, NKX3-1, ESR1, RBM39, APP, UTP20, NCSTN, SUPT16H, RBM14, SF3B6, SRSF11, TPR, SNRPD1, S100A9, RPS14, HNRNPM, IK, HNRNPC
Protein Size: 765 - 分子量
- 91 kDa
- 基因ID
- 7150
- NCBI登录号
- NM_003286, NP_003277
- UniProt
- P11387
- 途径
- Caspase Cascade in Apoptosis, Stem Cell Maintenance
-