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Topoisomerase I 抗体 (N-Term)

This anti-Topoisomerase I antibody is a 兔 多克隆 antibody detecting Topoisomerase I in WB. Suitable for 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔 和 犬.
产品编号 ABIN2788658
发货至: 中国

Quick Overview for Topoisomerase I 抗体 (N-Term) (ABIN2788658)

抗原

See all Topoisomerase I (TOP1) 抗体
Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

适用

  • 67
  • 28
  • 15
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 犬

宿主

  • 55
  • 12
  • 2

克隆类型

  • 45
  • 24
多克隆

标记

  • 42
  • 6
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This Topoisomerase I antibody is un-conjugated

应用范围

  • 45
  • 20
  • 19
  • 17
  • 16
  • 15
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 11
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    SNSEHKDSEK KHKEKEKTKH KDGSSEKHKD KHKDRDKEKR KEEKVRASGD

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

    产品特性

    This is a rabbit polyclonal antibody against TOP1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 765 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))

    别名

    TOP1

    背景

    This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
    Alias Symbols: TOPI
    Protein Interaction Partner: SUMO2, SUMO3, MDM2, UBC, SUMO1, ERG, RNF2, EED, SHFM1, CDK14, TARDBP, CDK2, HDAC9, EIF2AK2, PARP1, WHSC1, VCAM1, ITGA4, IL7R, VCP, PA2G4, NKX3-1, ESR1, RBM39, APP, UTP20, NCSTN, SUPT16H, RBM14, SF3B6, SRSF11, TPR, SNRPD1, S100A9, RPS14, HNRNPM, IK, HNRNPC
    Protein Size: 765

    分子量

    91 kDa

    基因ID

    7150

    NCBI登录号

    NM_003286, NP_003277

    UniProt

    P11387

    途径

    Caspase Cascade in Apoptosis, Stem Cell Maintenance
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