Histone H3.3 抗体 (N-Term)
Quick Overview for Histone H3.3 抗体 (N-Term) (ABIN2788643)
抗原
See all Histone H3.3 (H3F3A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- KSAPSTGGVK KPHRYRPGTV ALREIRRYQK STELLIRKLP FQRLVREIAQ
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预测反应
- Dog: 100%, Pig: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against H3f3a. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-H3 Histone, Family 3A (H3F3A) (AA 2-136) antibody
H3F3A 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-H3 Histone, Family 3A (H3F3A) (AA 1-137) antibodyH3F3A 适用: 人 ELISA, WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D7-H1 unconjugated
anti-H3 Histone, Family 3A (H3F3A) (Lys9) antibodyH3F3A 适用: 人 ELISA, WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-H3 Histone, Family 3A (H3F3A) (pThr3) antibodyH3F3A 适用: 人 ELISA, WB, ICC, FACS 宿主: 兔 Monoclonal 28H4 unconjugated Recombinant Antibody
anti-H3 Histone, Family 3A (H3F3A) antibodyH3F3A 适用: 人 ELISA, IHC, IF 宿主: 兔 Monoclonal 4H2 unconjugated Recombinant Antibody
anti-H3 Histone, Family 3A (H3F3A) antibodyH3F3A 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-H3 Histone, Family 3A (H3F3A) antibodyH3F3A 适用: 人 WB, IHC (p) 宿主: 兔 Monoclonal 7B12 unconjugated
anti-H3 Histone, Family 3A (H3F3A) (2meLys79) antibodyH3F3A 适用: 人 ELISA, WB, ChIP 宿主: 兔 Polyclonal unconjugated
anti-H3 Histone, Family 3A (H3F3A) (AA 100-150) antibodyH3F3A 适用: 人, 小鼠, Cow, Drosophila melanogaster, 马, 小鸡, Opossum WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-H3 Histone, Family 3A (H3F3A) antibodyMicroarray verified H3F3A 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB199456 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 126 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Histone H3.3 (H3F3A) (H3 Histone, Family 3A (H3F3A))
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别名
- H3f3a
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背景
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H3f3a is a variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. H3f3a constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. H3f3a is deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Alias Symbols: H3.3A, H3f3b, MGC102150
Protein Interaction Partner: Kmt2d, Chd5, Setd1a, Kmt2c, Setd1b, Ezh2, Chd1, Cbx3, Uhrf1, Nfkb2, Hdac5, Hdac3, Kdm6b, Nfe2, Aurka, Cbx2, Ehmt2, Cbx5, Aurkb, Cbx6, Bptf, Creb3l4, Ing2, Cbx7, Cbx8, Cbx4, Cd4, Fosb, Rps6ka5, Rps6ka3, Igh-8, Cd79a, Tcrb, Eif2s3x, Kdm5c, Nanog, Kcnq1ot1,
Protein Size: 126 -
分子量
- 15 kDa
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基因ID
- 15078
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NCBI登录号
- NM_008210, NP_032236
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UniProt
- P84244
抗原
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