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WHSC2 抗体 (N-Term)

This 兔 多克隆 anti-WHSC2 antibody specifically detects WHSC2 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 斑马鱼 和 Saccharomyces cerevisiae samples.
产品编号 ABIN2788623
发货至: 中国
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Quick Overview for WHSC2 抗体 (N-Term) (ABIN2788623)

抗原

See all WHSC2 抗体
WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

适用

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人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 斑马鱼, Saccharomyces cerevisiae

宿主

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克隆类型

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多克隆

标记

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This WHSC2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    LLRKERGVKL LDISELDMVG AGREAKRRRK TLDAEVVEKP AKEETVVENA

    预测反应

    Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against WHSC2. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N-terminal region of human NELFA
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))

    别名

    WHSC2

    背景

    This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
    Alias Symbols: WHSC2, NELF-A, P/OKcl.15
    Protein Size: 393

    分子量

    43 kDa

    基因ID

    7469

    NCBI登录号

    NM_005663, NP_005654

    UniProt

    Q9H3P2

    途径

    Chromatin Binding
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