WHSC2 抗体 (N-Term)
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Quick Overview for WHSC2 抗体 (N-Term) (ABIN2788623)
抗原
See all WHSC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- LLRKERGVKL LDISELDMVG AGREAKRRRK TLDAEVVEKP AKEETVVENA
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预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against WHSC2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of human NELFA
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- WHSC2 (Wolf-Hirschhorn Syndrome Candidate 2 (WHSC2))
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别名
- WHSC2
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背景
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This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93 % sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation.
Alias Symbols: WHSC2, NELF-A, P/OKcl.15
Protein Size: 393 -
分子量
- 43 kDa
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基因ID
- 7469
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NCBI登录号
- NM_005663, NP_005654
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UniProt
- Q9H3P2
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途径
- Chromatin Binding
抗原
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