IL-21 抗体 (C-Term)
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Quick Overview for IL-21 抗体 (C-Term) (ABIN2788558)
抗原
See all IL-21 (IL21) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- ERIINVSIKK LKRKPPSTNA GRRQKHRLTC PSCDSYEKKP PKEFLERFKS
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预测反应
- Cow: 79%, Dog: 86%, Goat: 86%, Horse: 79%, Human: 100%, Pig: 86%, Sheep: 86%
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产品特性
- This is a rabbit polyclonal antibody against IL21. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL21
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IL-21 (IL21) (Interleukin 21 (IL21))
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别名
- IL21
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背景
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This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: IL-21, Za11
Protein Interaction Partner: FBXO25, IL21R, DGKA,
Protein Size: 153 -
分子量
- 16 kDa
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基因ID
- 59067
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NCBI登录号
- NM_001207006, NP_001193935
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途径
- JAK/STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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