MAPKAP Kinase 2 抗体 (Middle Region)
Quick Overview for MAPKAP Kinase 2 抗体 (Middle Region) (ABIN2788401)
抗原
See all MAPKAP Kinase 2 (MAPKAPK2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- KLTDFGFAKE TTQNALQTPC YTPYYVAPEV LGPEKYDKSC DMWSLGVIMY
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against MAPKAPK2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MAPKAPK2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 370 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
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别名
- MAPKAPK2
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背景
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MAPKAPK2 is a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo.
Alias Symbols: 3PK, MAPKAP3, MK2, MK-2, MAPKAP-K2
Protein Interaction Partner: PIAS2, DDX5, MAPK14, AKT1, HSPB1, MAPKAPK2, UBC, Ube2j1, TCF3, DES, MAP2K6, MAPK11, MAPK3, PABPC1, HNRNPA0, PARN, LIMK1, HSF1, CHEK1, CDC25B, ALOX5, ZFP36L1, ESR1, COPS5, CUL3, MAPKAPK5, MAPK1, ELAVL1, PHC2, CSNK2B, ARPC5, EEF2K, BAG2, YWHAZ, SRF, SHC1, E
Protein Size: 370 -
分子量
- 42 kDa
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基因ID
- 9261
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NCBI登录号
- NM_004635, NP_004626
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UniProt
- Q16644
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades
抗原
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