DDB2 抗体 (C-Term)
Quick Overview for DDB2 抗体 (C-Term) (ABIN2788357)
抗原
See all DDB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- IVVGRYPDPN FKSCTPYELR TIDVFDGNSG KMMCQLYDPE SSGISSLNEF
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预测反应
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 79%, Rabbit: 93%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against DDB2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human DDB2
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anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 1-315) antibody
DDB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 201-300) antibodyDDB2 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) antibodyDDB2 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 166-383) antibodyDDB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 1-427) antibodyDDB2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) antibodyDDB2 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 2246C4a unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) antibodyDDB2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 1-185) antibodyDDB2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (AA 1-109) antibodyDDB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-Damage-Specific DNA Binding Protein 2, 48kDa (DDB2) (C-Term) antibodyDDB2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 427 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- DDB2 (Damage-Specific DNA Binding Protein 2, 48kDa (DDB2))
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别名
- DDB2
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背景
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This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities.
Alias Symbols: DDBB, FLJ34321, UV-DDB2
Protein Interaction Partner: CUL4A, CUL4B, XPC, PARP1, UBC, SUMO1, SMEK1, COPG1, POP1, PSMB4, PSMB1, PSMA5, SEPT2, ARCN1, SUMO2, DDB1, USP24, USP53, RFWD2, COPS4, COPS6, COPS2, COPS3, XPA, TOP1, GRK5, EP300, COPS7A, COPS5, COPS8, RBX1, GPS1, E2F1, DDB2, CUL5, NEDD8, DCLRE1C, vpr, ERC
Protein Size: 427 -
分子量
- 48 kDa
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基因ID
- 1643
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NCBI登录号
- NM_000107, NP_000098
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UniProt
- Q92466
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途径
- DNA Damage Repair
抗原
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