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FGFR2 抗体 (Middle Region)

FGFR2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788320
发货至: 中国
  • 抗原 See all FGFR2 抗体
    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
    抗原表位
    • 16
    • 14
    • 13
    • 10
    • 10
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 125
    • 66
    • 45
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, 绵羊
    宿主
    • 118
    • 6
    • 1
    克隆类型
    • 110
    • 15
    多克隆
    标记
    • 52
    • 13
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FGFR2 antibody is un-conjugated
    应用范围
    • 73
    • 53
    • 46
    • 36
    • 26
    • 19
    • 13
    • 13
    • 11
    • 10
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    KHVEKNGSKY GPDGLPYLKV LKHSGINSSN AEVLALFNVT EADAGEYICK
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 91%
    产品特性
    This is a rabbit polyclonal antibody against FGFR2. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the middle region of human FGFR2
    Top Product
    Discover our top product FGFR2 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 705 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    FGFR2 (Fibroblast Growth Factor Receptor 2 (FGFR2))
    别名
    FGFR2 (FGFR2 产品)
    别名
    FGFR2 antibody, FGFR2IIIb antibody, bek antibody, bfr-1 antibody, cd332 antibody, cek3 antibody, cfd1 antibody, ect1 antibody, fgfr-2 antibody, jws antibody, k-sam antibody, kgfr antibody, tk14 antibody, tk25 antibody, xfgfr2 antibody, DKFZp469H1521 antibody, BBDS antibody, BEK antibody, BFR-1 antibody, CD332 antibody, CEK3 antibody, CFD1 antibody, ECT1 antibody, JWS antibody, K-SAM antibody, KGFR antibody, TK14 antibody, TK25 antibody, AU043015 antibody, AW556123 antibody, Bek antibody, Fgfr-2 antibody, Fgfr-7 antibody, Fgfr7 antibody, KGFRTr antibody, svs antibody, FGF-R antibody, fgfr72IIIb antibody, FGFR antibody, fc56c05 antibody, wu:fc56c05 antibody, fibroblast growth factor receptor 2 antibody, fibroblast growth factor receptor 2 L homeolog antibody, FGFR2 antibody, LOC100084641 antibody, fgfr2 antibody, Fgfr2 antibody, fgfr2.L antibody
    背景
    The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
    Alias Symbols: BEK, BFR-1, CD332, CEK3, CFD1, ECT1, FLJ98662, JWS, K-SAM, KGFR, TK14, TK25
    Protein Interaction Partner: PPM1A, APP, HGS, UBC, LYN, FYN, CBL, NEDD4, FRS2, STAT5B, STAT5A, PGR, STAT3, ITGA5, PAK4, FGF23, FGF18, FGF17, EPHA4, FGF10, PTK2B, FGF9, FGF8, PLCG1, FGF5, FGF4, FGF3, FGF7, FGF6, FGF1, CACNA1D, PIK3R1, FGFR2,
    Protein Size: 705
    分子量
    78 kDa
    基因ID
    2263
    NCBI登录号
    NM_022970, NP_075259
    UniProt
    P21802
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Growth Factor Binding
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