Factor VII 抗体 (Middle Region)
Quick Overview for Factor VII 抗体 (Middle Region) (ABIN2788317)
抗原
See all Factor VII (F7) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- RCHEGYSLLA DGVSCTPTVE YPCGKIPILE KRNASKPQGR IVGGKVCPKG
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预测反应
- Cow: 86%, Horse: 86%, Human: 100%, Pig: 79%, Rabbit: 85%, Rat: 83%
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产品特性
- This is a rabbit polyclonal antibody against F7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human F7
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anti-Coagulation Factor VII (F7) (AA 42-169) antibody
F7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 1-444) antibodyF7 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 1-444) antibodyF7 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 209-444) antibodyF7 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) antibodyF7 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 334-452) antibodyF7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 315-433) antibodyF7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 334-452) antibodyF7 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 1# unconjugated
anti-Coagulation Factor VII (F7) (AA 193-447) antibodyF7 适用: Cow WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor VII (F7) (AA 302-332) antibodyF7 适用: 人 WB 宿主: 兔 Polyclonal RB54990 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 466 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Factor VII (F7) (Coagulation Factor VII (F7))
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别名
- F7
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背景
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This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy.
Alias Symbols: SPCA
Protein Interaction Partner: FUS, CEP76, CEP250, VCP, RCHY1, ALB, UIMC1, USP49, DMWD, F9, F10, F7, HPN, GGCX, F3,
Protein Size: 466 -
分子量
- 52 kDa
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基因ID
- 2155
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NCBI登录号
- NM_000131, NP_000122
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UniProt
- P08709
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途径
- Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling
抗原
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