Factor VII 抗体 (Middle Region)
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- 抗原 See all Factor VII (F7) 抗体
- Factor VII (F7) (Coagulation Factor VII (F7))
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抗原表位
- Middle Region
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适用
- 人, 大鼠, Cow, 兔, Pig, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Factor VII antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RCHEGYSLLA DGVSCTPTVE YPCGKIPILE KRNASKPQGR IVGGKVCPKG
- 预测反应
- Cow: 86%, Horse: 86%, Human: 100%, Pig: 79%, Rabbit: 85%, Rat: 83%
- 产品特性
- This is a rabbit polyclonal antibody against F7. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human F7
- Top Product
- Discover our top product F7 Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 466 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Factor VII (F7) (Coagulation Factor VII (F7))
- 别名
- F7 (F7 产品)
- 背景
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This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy.
Alias Symbols: SPCA
Protein Interaction Partner: FUS, CEP76, CEP250, VCP, RCHY1, ALB, UIMC1, USP49, DMWD, F9, F10, F7, HPN, GGCX, F3,
Protein Size: 466 - 分子量
- 52 kDa
- 基因ID
- 2155
- NCBI登录号
- NM_000131, NP_000122
- UniProt
- P08709
- 途径
- Response to Growth Hormone Stimulus, Platelet-derived growth Factor Receptor Signaling
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