F2RL1 抗体 (C-Term)
(1 reference)Quick Overview for F2RL1 抗体 (C-Term) (ABIN2788314)
抗原
See all F2RL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VSHDFRDHAK NALLCRSVRT VKQMQVSLTS KKHSRKSSSY SSSSTTVKTS
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预测反应
- Dog: 93%, Guinea Pig: 86%, Human: 100%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against F2RL1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 368-382), (Intracellular) antibody
F2RL1 适用: 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) antibodyF2RL1 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) antibodyF2RL1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 348-397) antibodyF2RL1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 218-399) antibodyF2RL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (N-Term) antibodyF2RL1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (Extracellular Domain) antibodyF2RL1 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (N-Term) antibodyF2RL1 适用: 人 ELISA, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal SAM11 unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (C-Term) antibodyF2RL1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1) (AA 260-309) antibodyF2RL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 397 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Toward drugs for protease-activated receptor 2 (PAR2)." in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).
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: "Toward drugs for protease-activated receptor 2 (PAR2)." in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).
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- F2RL1 (Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
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别名
- F2RL1
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背景
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Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence.
Alias Symbols: GPR11, PAR2
Protein Interaction Partner: BIRC5, COPS5, UBC, Cbl, ST14, GPRASP1, PRTN3, F2, PLG, ELANE, CTSG, CAPN2, CAPN1,
Protein Size: 397 -
分子量
- 44 kDa
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基因ID
- 2150
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NCBI登录号
- NM_005242, NP_005233
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UniProt
- P55085
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, SARS-CoV-2 Protein Interactome
抗原
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