CMA1 抗体 (C-Term)
Quick Overview for CMA1 抗体 (C-Term) (ABIN2788295)
抗原
See all CMA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- EVKLRLMDPQ ACSHFRDFDH NLQLCVGNPR KTKSAFKGDS GGPLLCAGVA
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预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 79%, Rabbit: 79%, Rat: 86%, Sheep: 86%
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产品特性
- This is a rabbit polyclonal antibody against CMA1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CMA1
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anti-Chymase 1, Mast Cell (CMA1) (Internal Region) antibody
Verified CMA1 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) antibodyCMA1 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (C-Term) antibodyCMA1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-247) antibodyCMA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 9-247) antibodyCMA1 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 1-247) antibodyCMA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-247) antibodyCMA1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 22-197) antibodyCMA1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Chymase 1, Mast Cell (CMA1) (AA 84-118) antibodyCMA1 适用: 人 WB 宿主: 兔 Polyclonal RB53046 unconjugated
anti-Chymase 1, Mast Cell (CMA1) antibodyCMA1 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 247 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CMA1 (Chymase 1, Mast Cell (CMA1))
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别名
- CMA1
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背景
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CMA1 is a chymotryptic serine proteinase that belongs to the peptidase family S1. It is expressed in mast cells and thought to function in the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. In the heart and blood vessels, this protein, rather than angiotensin converting enzyme, is largely responsible for converting angiotensin I to the vasoactive peptide angiotensin II. Angiotensin II has been implicated in blood pressure control and in the pathogenesis of hypertension, cardiac hypertrophy, and heart failure. Thus, this gene product is a target for cardiovascular disease therapies.
Alias Symbols: CYH, MCT1, MGC119890, MGC119891, chymase
Protein Interaction Partner: FYN, IL1B, EDN2, EDN1, KITLG, PFN1, EDN3, MMP1, SERPINA3, AGT,
Protein Size: 247 -
分子量
- 27 kDa
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基因ID
- 1215
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NCBI登录号
- NM_001836, NP_001827
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UniProt
- P23946
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途径
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Carbohydrate Homeostasis
抗原
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