BTBD12 抗体 (N-Term)
Quick Overview for BTBD12 抗体 (N-Term) (ABIN2788239)
抗原
See all BTBD12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- TKTLQGPAEK KPPSGSQAPR TKKQRVTKWQ ASEPAHSVNG EGGVLASAPD
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预测反应
- Human: 100%, Rabbit: 91%
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产品特性
- This is a rabbit polyclonal antibody against BTBD12. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human BTBD12
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anti-BTB (POZ) Domain Containing 12 (BTBD12) (AA 1-1151) antibody
BTBD12 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-BTB (POZ) Domain Containing 12 (BTBD12) (AA 100-149) antibodyBTBD12 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-BTB (POZ) Domain Containing 12 (BTBD12) (AA 1784-1834) antibodyBTBD12 适用: 人 IP, IHC (p), IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-BTB (POZ) Domain Containing 12 (BTBD12) (N-Term) antibodyBTBD12 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1834 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))
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别名
- BTBD12
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背景
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This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.
Alias Symbols: KIAA1784, KIAA1987, MUS312, SLX4, FANCP, BTBD12
Protein Interaction Partner: MUS81, vpr, SLX1A, SLX1B, DCLRE1B, TERF2, ERCC4, UBC, ERCC1, APP, EME1, PCNA, MSH2, MSH6, DDB1, SLX4IP, SPRTN, TERF2IP, VCP, PLK1, SUMO2, PGAM5, DCAF10, LRRC1, GID8, TEX10, GLTSCR2, NUP188, NUP50, PNMA2, TSPYL1, PSMB4, MSH3, KPNA1,
Protein Size: 1834 -
分子量
- 200 kDa
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基因ID
- 84464
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NCBI登录号
- NM_032444, NP_115820
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UniProt
- Q8IY92
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途径
- DNA Damage Repair
抗原
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