ARHGEF2 抗体 (C-Term)
Quick Overview for ARHGEF2 抗体 (C-Term) (ABIN2788156)
抗原
See all ARHGEF2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- NTSPGVTANG EARTFNGSIE LCRADSDSSQ RDRNGNQLRS PQEEALQRLV
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预测反应
- Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against ARHGEF2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human ARHGEF2
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 986 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))
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别名
- ARHGEF2
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背景
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Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: DKFZp547L106, DKFZp547P1516, FLJ45440, GEF, GEF-H1, GEFH1, KIAA0651, LFP40, P40
Protein Interaction Partner: RPP25L, UBC, CEP250, RPA3, RPA2, RPA1, PPP6C, FBXO6, ANKRD28, PPP6R1, YWHAB, MMS19, PEX14, VCP, NOTCH1, YWHAZ, MARK2, RHOA, AKT1, USP21, ELAVL1, SUMO1, MARK4, YWHAH, YWHAG, MYC, MAPK1, TAF10, CGN, YWHAE, PAK1, RAC1, RRAS2, PLCG1, WASF1, YWHAQ,
Protein Size: 986 -
分子量
- 111 kDa
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基因ID
- 9181
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NCBI登录号
- NM_001162383, NP_001155855
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UniProt
- Q92974
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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