Metabotropic Glutamate Receptor 3 抗体 (C-Term)
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- 抗原 See all Metabotropic Glutamate Receptor 3 (GRM3) 抗体
- Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠, Cow, 马, 兔, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Metabotropic Glutamate Receptor 3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RDFWEQKFQC SLQNKRNHRR VCDKHLAIDS SNYEQESKIM FVVNAVYAMA
- 预测反应
- Cow: 92%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 93%
- 产品特性
- This is a rabbit polyclonal antibody against GRM3. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of human GRM3
- Top Product
- Discover our top product GRM3 Primary Antibody
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- Metabotropic Glutamate Receptor 3 (GRM3) (Glutamate Receptor, Metabotropic 3 (GRM3))
- 别名
- GRM3 (GRM3 产品)
- 背景
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L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.
Alias Symbols: GLUR3, mGlu3, GPRC1C, MGLUR3
Protein Size: 537 - 分子量
- 59 kDa
- 基因ID
- 2913
- NCBI登录号
- NM_000840, NP_000831
- UniProt
- Q14832
- 途径
- cAMP Metabolic Process, Synaptic Membrane
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