UFD1L 抗体 (Middle Region)
Quick Overview for UFD1L 抗体 (Middle Region) (ABIN2788062)
抗原
See all UFD1L 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NYNEKIYELR VMETKPDKAV SIIECDMNVD FDAPLGYKEP ERQVQHEEST
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against UFD1L. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human UFD1L
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 307 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))
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别名
- UFD1L
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背景
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The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.
Alias Symbols: UFD1
Protein Interaction Partner: HUWE1, YOD1, VCP, UBC, SHFM1, SUZ12, BTRC, EZH2, PDCD4, NPLOC4, NFKBIA, NUB1, NEDD8, CAV1, ADRB2, FAF1, TXLNA, UNC45A, VPS33B, UBE3A, UBE2N, PSMD7, SPRTN, UBXN6, GZMK, ERLIN2, ITPR1, PPHLN1, ANAPC2, TIAM2, TAF1C, TP53, SNX1, MASP1, PIK3CA, NGFR, IGHM, F13
Protein Size: 307 -
分子量
- 34 kDa
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基因ID
- 7353
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NCBI登录号
- NM_005659, NP_005650
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UniProt
- Q92890
抗原
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