NAE1 抗体 (C-Term)
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- 抗原 See all NAE1 抗体
- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
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抗原表位
- C-Term
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 马, Pig, 兔, 斑马鱼
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NAE1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- ARALKEFVAK EGQGNLPVRG TIPDMIADSN KYIKLQNVYR EKAKKDAAAV
- 预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
- 产品特性
- This is a rabbit polyclonal antibody against Nae1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Nae1
- Top Product
- Discover our top product NAE1 Primary Antibody
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anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) antibody
NAE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E8-H3 unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-220), (Regulatory Subunit) antibodyNAE1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) antibodyNAE1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) antibodyNAE1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 430-459), (C-Term) antibodyNAE1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB8977 unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (C-Term) antibodyNAE1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) antibodyNAE1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 308-357) antibodyNAE1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) antibodyNAE1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 172-200) antibodyNAE1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33003 unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 534 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
- 别名
- Nae1 (NAE1 产品)
- 别名
- APPBP1 antibody, CG7828 antibody, Dmel\\CG7828 antibody, anon-WO0140519.225 antibody, dAPP-BP1 antibody, dAPPBP1 antibody, A-116A10.1 antibody, ula-1 antibody, Appbp1 antibody, 59kDa antibody, appbp1 antibody, zgc:66148 antibody, beta-Amyloid precursor protein binding protein 1 antibody, NEDD8 activating enzyme E1 subunit 1 antibody, NEDD8 activating enzyme E1 subunit 1 S homeolog antibody, nedd8 activating enzyme E1 subunit 1 antibody, NEDD8-activating enzyme E1 regulatory subunit antibody, APP-BP1 antibody, NAE1 antibody, Nae1 antibody, nae1.S antibody, nae1 antibody, ula-1 antibody
- 背景
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Nae1 is a regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
Alias Symbols: 59 kDa, Appbp1
Protein Size: 534 - 分子量
- 60 kDa
- 基因ID
- 234664
- NCBI登录号
- NM_144931, NP_659180
- UniProt
- Q8VBW6
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