NAE1 抗体 (C-Term)
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北京 101111
Quick Overview for NAE1 抗体 (C-Term) (ABIN2788045)
抗原
See all NAE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Nae1 Antibody - C-terminal region
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序列
- ARALKEFVAK EGQGNLPVRG TIPDMIADSN KYIKLQNVYR EKAKKDAAAV
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预测反应
- Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%
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产品特性
- This is a rabbit polyclonal antibody against Nae1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Nae1
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anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 229-534) antibody
NAE1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) antibodyNAE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E8-H3 unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 430-459), (C-Term) antibodyNAE1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB8977 unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 172-200) antibodyNAE1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33003 unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-220), (Regulatory Subunit) antibodyNAE1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) antibodyKD Validated NAE1 适用: 人 WB 宿主: 小鼠 Monoclonal 24GB13290 unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) antibodyNAE1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) antibodyNAE1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (N-Term) antibodyNAE1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) antibodyNAE1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59379-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
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别名
- Nae1
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背景
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Background Information: Nae1 is a regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
Gene Name: NEDD8 activating enzyme E1 subunit 1
Alternative Symbols: Ap, 59 kDa, Appbp1
Protein Name: NEDD8-activating enzyme E1 regulatory subunit
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分子量
- 60kDa
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基因ID
- 234664
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NCBI登录号
- NP_659180
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UniProt
- Q8VBW6
抗原
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