Interleukin 17a 抗体 (N-Term)
Quick Overview for Interleukin 17a 抗体 (N-Term) (ABIN2787948)
抗原
See all Interleukin 17a (IL17A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- MTPGKTSLVS LLLLLSLEAI VKAGITIPRN PGCPNSEDKN FPRTVMVNLN
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预测反应
- Cow: 83%, Dog: 85%, Goat: 83%, Horse: 77%, Human: 100%, Pig: 83%, Rabbit: 92%, Rat: 75%
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产品特性
- This is a rabbit polyclonal antibody against IL17A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human IL17A
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 155 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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别名
- IL17A
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背景
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The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Alias Symbols: CTLA8, IL-17, IL-17A, IL17
Protein Interaction Partner: DPH2, TRAF3IP2, TRAF6, IL17RA, IL17A,
Protein Size: 155 -
分子量
- 15 kDa
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基因ID
- 3605
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NCBI登录号
- NM_002190, NP_002181
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UniProt
- Q16552
抗原
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