CD4 抗体 (C-Term)
Quick Overview for CD4 抗体 (C-Term) (ABIN2787938)
抗原
See all CD4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- VLGGVAGLLL FIGLGIFFCV RCRHRRRQAE RMSQIKRLLS EKKTCQCPHR
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预测反应
- Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%
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产品特性
- This is a rabbit polyclonal antibody against CD4. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CD4
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 458 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD4
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别名
- CD4
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背景
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This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
Alias Symbols: CD4mut
Protein Interaction Partner: env, RANBP9, vpu, ADRB2, UBC, CXCR4, UBL7, ABCB1, INPPL1, VCP, HGS, LCK, NR3C1, STUB1, TUBB, MYL12A, DHRS2, LRPPRC, FARSB, EIF3I, EIF3D, EIF3C, EIF3B, VIM, VDAC3, VDAC2, VDAC1, SSRP1, RPS19, RPS12, RPS10, RPS9, RPLP1, RPLP0, RPL22, RPL18, RPL7, PHB, NPM1,
Protein Size: 458 -
分子量
- 48 kDa
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基因ID
- 920
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NCBI登录号
- NM_000616, NP_000607
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UniProt
- P01730
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途径
- TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
抗原
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