ATG7 抗体 (C-Term)
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北京 101111
Quick Overview for ATG7 抗体 (C-Term) (ABIN2787928)
抗原
See all ATG7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Atg7 Antibody - C-terminal region
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序列
- KLVINAALGF DTFVVMRHGL KKPKQQGAGD LCPSHLVAPA DLGSSLFANI
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预测反应
- Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Atg7. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Rat Atg7
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59072-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- ATG7 (ATG7 Autophagy Related 7 (ATG7))
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别名
- Atg7
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背景
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Background Information: Atg7 functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. It forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. It also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3.
Gene Name: autophagy related 7
Alternative Symbols: Apg7l
Protein Name: Ubiquitin-like modifier-activating enzyme ATG7
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分子量
- 76kDa
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基因ID
- 312647
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NCBI登录号
- NP_001012097
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UniProt
- Q641Y5
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途径
- Response to Water Deprivation, Autophagy
抗原
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