NCF4 抗体 (C-Term)
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北京 101111
Quick Overview for NCF4 抗体 (C-Term) (ABIN567428)
抗原
See all NCF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- PSLRPLPLTS PSHGSLSHSK APSGSQMSHN AVTSHQRPGW PGQPHSPFPH
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against NCF4. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NCF4
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anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 111-339) antibody
NCF4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (Internal Region) antibodyVerified NCF4 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) antibodyNCF4 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (C-Term) antibodyNCF4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-190) antibodyNCF4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 260-289), (C-Term) antibodyNCF4 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18508 unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-339) antibodyNCF4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-339) antibodyNCF4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 136-239) antibodyNCF4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) antibodyNCF4 适用: 人 WB, ICC 宿主: 兔 Monoclonal 24GB45 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 348 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
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别名
- NCF4
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背景
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NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC3810, NCF, P40PHOX, SH3PXD4
Protein Interaction Partner: NCF2, UBC, CORO1A, MSN, CYBB, NCF1, CYBA, TXN, PRKCD, XRCC6, PRKDC,
Protein Size: 348 -
分子量
- 39 kDa
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基因ID
- 4689
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NCBI登录号
- NM_013416, NP_038202
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UniProt
- A8K4F9
抗原
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