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- 抗原 See all NCF4 抗体
- NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NCF4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PSLRPLPLTS PSHGSLSHSK APSGSQMSHN AVTSHQRPGW PGQPHSPFPH
- 预测反应
- Human: 100%
- 产品特性
- This is a rabbit polyclonal antibody against NCF4. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human NCF4
- Top Product
- Discover our top product NCF4 Primary Antibody
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anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 111-339) antibody
NCF4 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (Internal Region) antibodyVerified NCF4 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) antibodyNCF4 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (C-Term) antibodyNCF4 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-190) antibodyNCF4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 136-239) antibodyNCF4 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-339) antibodyNCF4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 1-339) antibodyNCF4 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) (AA 260-289), (C-Term) antibodyNCF4 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB18508 unconjugated
anti-Neutrophil Cytosolic Factor 4, 40kDa (NCF4) antibodyNCF4 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 348 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- NCF4 (Neutrophil Cytosolic Factor 4, 40kDa (NCF4))
- 别名
- NCF4 (NCF4 产品)
- 别名
- p40phox antibody, AI451400 antibody, NCF antibody, P40PHOX antibody, SH3PXD4 antibody, neutrophil cytosolic factor 4 antibody, ncf4 antibody, Ncf4 antibody, NCF4 antibody
- 背景
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NCF4 is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Alias Symbols: MGC3810, NCF, P40PHOX, SH3PXD4
Protein Interaction Partner: NCF2, UBC, CORO1A, MSN, CYBB, NCF1, CYBA, TXN, PRKCD, XRCC6, PRKDC,
Protein Size: 348 - 分子量
- 39 kDa
- 基因ID
- 4689
- NCBI登录号
- NM_013416, NP_038202
- UniProt
- A8K4F9
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