APP 抗体 (C-Term)
Quick Overview for APP 抗体 (C-Term) (ABIN2787850)
抗原
See all APP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LVMLKKKQYT SIHHGVVEVD AAVTPEERHL SKMQQNGYEN PTYKFFEQMQ
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against App. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human App
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 751 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- APP (Amyloid beta (A4) Precursor Protein (APP))
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别名
- App
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背景
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App functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. It is involved in cell mobility and transcription regulation through protein-protein interactions.
Alias Symbols: Abeta, Abpp, Adap, Ag, betaApp, Cvap, E030013M08Rik
Protein Interaction Partner: Ranbp9, Cpeb1, Bace1, Snca, Prnp, Gga1, Stub1, Ubc, Kif1a, Mme, Mapk8ip2, Mapk8ip1, Dab1,
Protein Size: 751 -
分子量
- 83 kDa
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基因ID
- 11820
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NCBI登录号
- NM_001198824, NP_001185753
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UniProt
- P12023
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途径
- Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour
抗原
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