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BPNT1 抗体 (N-Term)

BPNT1 适用: 人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Pig WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787757
发货至: 中国
  • 抗原 See all BPNT1 抗体
    BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
    抗原表位
    • 16
    • 9
    • 8
    • 7
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 小鼠, 大鼠, Cow, 兔, 犬, 豚鼠, 马, Pig
    宿主
    • 35
    • 2
    • 1
    克隆类型
    • 37
    • 1
    多克隆
    标记
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This BPNT1 antibody is un-conjugated
    应用范围
    • 38
    • 17
    • 14
    • 13
    • 13
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    DRVTIQELTA PLLTTAQAKP GETQEEETNS GEEPFIETPR QDGVSRRFIP
    预测反应
    Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 91%
    产品特性
    This is a rabbit polyclonal antibody against BPNT1. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human BPNT1
    Top Product
    Discover our top product BPNT1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 261 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
    别名
    BPNT1 (BPNT1 产品)
    别名
    BPNT1 antibody, PIP antibody, Sal3 antibody, BPntase antibody, 3'(2'), 5'-bisphosphate nucleotidase 1 antibody, bisphosphate 3'-nucleotidase 1 antibody, BPNT1 antibody, bpnt1.L antibody, Bpnt1 antibody
    背景
    BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
    Alias Symbols: PIP
    Protein Interaction Partner: SUMO2, UBC, IQCB1,
    Protein Size: 261
    分子量
    29 kDa
    基因ID
    10380
    NCBI登录号
    NM_006085, NP_006076
    UniProt
    O95861
    途径
    Inositol Metabolic Process
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