BPNT1 抗体 (N-Term)
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北京 101111
Quick Overview for BPNT1 抗体 (N-Term) (ABIN2787757)
抗原
See all BPNT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DRVTIQELTA PLLTTAQAKP GETQEEETNS GEEPFIETPR QDGVSRRFIP
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预测反应
- Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 100%, Rat: 91%
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产品特性
- This is a rabbit polyclonal antibody against BPNT1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human BPNT1
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anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 1-100) antibody
BPNT1 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 2E1 unconjugated
anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) antibodyBPNT1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (C-Term) antibodyVerified BPNT1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 1-261) antibodyBPNT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 35-84) antibodyBPNT1 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1) (AA 7-308) antibodyBPNT1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 261 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BPNT1 (3'(2'), 5'-Bisphosphate Nucleotidase 1 (BPNT1))
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别名
- BPNT1
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背景
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BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92 % identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.
Alias Symbols: PIP
Protein Interaction Partner: SUMO2, UBC, IQCB1,
Protein Size: 261 -
分子量
- 29 kDa
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基因ID
- 10380
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NCBI登录号
- NM_006085, NP_006076
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UniProt
- O95861
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途径
- Inositol Metabolic Process
抗原
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