PPP4C 抗体 (Middle Region)
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北京 101111
Quick Overview for PPP4C 抗体 (Middle Region) (ABIN2787719)
抗原
See all PPP4C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- PPP4C Antibody - middle region
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序列
- TVLTVWSAPN YCYRCGNVAA ILELDEHLQK DFIIFEAAPQ ETRGIPSKKP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against PPP4C. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human PPP4C
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anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibody
PPP4C 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-50) antibodyPPP4C 适用: 人, 小鼠 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 265-307) antibodyPPP4C 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (C-Term) antibodyVerified PPP4C 适用: 人, 大鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-307) antibodyPPP4C 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) antibodyKD Validated PPP4C 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB13365 unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) antibodyKD Validated PPP4C 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 24GB13370 unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 160-189) antibodyPPP4C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33771 unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (C-Term) antibodyPPP4C 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 4, Catalytic Subunit (PPP4C) (AA 1-50) antibodyPPP4C 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58516-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- PPP4C (Protein Phosphatase 4, Catalytic Subunit (PPP4C))
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别名
- PPP4C
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背景
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Background Information: PPP4C is a protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. Dephosphorylates NDEL1 at CDC2/Cdk1 phosphorylation sites and negatively regulates CDC2/Cdk1 activity in interphase.
Gene Name: Protein phosphatase 4, catalytic subunit
Alternative Symbols: PP4, PPX, PP-X, PP4C, PPH3, PPP4
Protein Name: Serine/threonine-protein phosphatase 4 catalytic subunit
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分子量
- 34kDa
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基因ID
- 5531
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NCBI登录号
- NP_002711
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UniProt
- P60510
抗原
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