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Dynamitin 抗体 (N-Term)

This anti-Dynamitin antibody is a 兔 多克隆 antibody detecting Dynamitin in WB. Suitable for 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠 和 斑马鱼.
产品编号 ABIN2787686
发货至: 中国

Quick Overview for Dynamitin 抗体 (N-Term) (ABIN2787686)

抗原

See all Dynamitin (DCTN2) 抗体
Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

适用

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人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼

宿主

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克隆类型

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多克隆

标记

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This Dynamitin antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    序列

    ADPKYADLPG IARNEPDVYE TSDLPEDDQA EFDAFAQELE ELTSTSVEHI

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against DCTN2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DCTN2
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 406 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Dynamitin (DCTN2) (Dynactin 2 (p50) (DCTN2))

    别名

    DCTN2

    背景

    DCTN2 is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: DCTN50, DYNAMITIN, RBP50
    Protein Interaction Partner: KIFC3, CCDC172, HAUS1, BLOC1S6, DCTN2, BICD2, DYNC1I1, DCTN1, UBC, FLNB, NUP43, LEO1, SEH1L, ACTR10, DCTN4, DCTN3, ACTR1A, ACTR1B, RABEP1, LMNB1, GADD45A, KPNA2, SMURF1, DYNLRB1, STRN4, RANBP9, TPM4, SNRPA1, PSMD4, PSMD1, PSMC4, PSMC2, POLR2D, POLR2A, MCM
    Protein Size: 406

    分子量

    45 kDa

    基因ID

    10540

    NCBI登录号

    NM_006400, NP_006391

    UniProt

    Q13561

    途径

    M Phase, Ribonucleoprotein Complex Subunit Organization
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