APRT 抗体 (N-Term)
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- 抗原 See all APRT 抗体
- APRT (Adenine Phosphoribosyltransferase (APRT))
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抗原表位
- N-Term
- 适用
- 人, 大鼠, 犬, Cow, 豚鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This APRT antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 序列
- ADSELQLVEQ RIRSFPDFPT PGVVFRDISP VLKDPASFRA AIGLLARHLK
- 预测反应
- Cow: 79%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Rat: 77%
- 产品特性
- This is a rabbit polyclonal antibody against APRT. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human APRT
- Top Product
- Discover our top product APRT Primary Antibody
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 180 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- APRT (Adenine Phosphoribosyltransferase (APRT))
- 别名
- APRT (APRT 产品)
- 别名
- Tb07.43M14.200 antibody, Tb07.43M14.180 antibody, C85684 antibody, AMP antibody, APRTD antibody, adenine phosphoribosyltransferase antibody, adenine phosphoribosyl transferase antibody, CND05020 antibody, Tb927.7.1790 antibody, Tb927.7.1780 antibody, Arnit_0941 antibody, Saut_1231 antibody, Fbal_1180 antibody, PH_RS07970 antibody, PF_RS08760 antibody, PAB_RS02560 antibody, Aprt antibody, APRT antibody
- 背景
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Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961
Protein Interaction Partner: UBC, FN1, VCAM1, MLH1, ITGA4, NAPRT, HECW2, GMPS, UMPS, HPRT1, APP, IKBKG, APRT, VHL,
Protein Size: 180 - 分子量
- 20 kDa
- 基因ID
- 353
- NCBI登录号
- NM_000485, NP_000476
- UniProt
- P07741
- 途径
- Ribonucleoside Biosynthetic Process
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