APRT 抗体 (N-Term)
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北京 101111
Quick Overview for APRT 抗体 (N-Term) (ABIN2787672)
抗原
See all APRT 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- APRT Antibody - N-terminal region
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序列
- ADSELQLVEQ RIRSFPDFPT PGVVFRDISP VLKDPASFRA AIGLLARHLK
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预测反应
- Cow: 79%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Rat: 77%
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产品特性
- This is a rabbit polyclonal antibody against APRT. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human APRT
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58422-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- APRT (Adenine Phosphoribosyltransferase (APRT))
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别名
- APRT
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背景
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Background Information: Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: Adenine phosphoribosyltransferase
Alternative Symbols: AMP, APRTD
Protein Name: Adenine phosphoribosyltransferase
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分子量
- 20kDa
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基因ID
- 353
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NCBI登录号
- NP_000476
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UniProt
- P07741
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途径
- Ribonucleoside Biosynthetic Process
抗原
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