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APRT 抗体 (N-Term)

APRT 适用: 人, 大鼠, 犬, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2787672
发货至: 中国
  • 抗原 See all APRT 抗体
    APRT (Adenine Phosphoribosyltransferase (APRT))
    抗原表位
    • 13
    • 10
    • 8
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    人, 大鼠, 犬, Cow, 豚鼠
    宿主
    • 57
    • 3
    克隆类型
    • 59
    • 1
    多克隆
    标记
    • 29
    • 5
    • 5
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APRT antibody is un-conjugated
    应用范围
    • 47
    • 28
    • 25
    • 9
    • 8
    • 7
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    ADSELQLVEQ RIRSFPDFPT PGVVFRDISP VLKDPASFRA AIGLLARHLK
    预测反应
    Cow: 79%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Rat: 77%
    产品特性
    This is a rabbit polyclonal antibody against APRT. It was validated on Western Blot using a cell lysate as a positive control.
    纯化方法
    Affinity Purified
    免疫原
    The immunogen is a synthetic peptide directed towards the N terminal region of human APRT
    Top Product
    Discover our top product APRT Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 180 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    APRT (Adenine Phosphoribosyltransferase (APRT))
    别名
    APRT (APRT 产品)
    别名
    Tb07.43M14.200 antibody, Tb07.43M14.180 antibody, C85684 antibody, AMP antibody, APRTD antibody, adenine phosphoribosyltransferase antibody, adenine phosphoribosyl transferase antibody, CND05020 antibody, Tb927.7.1790 antibody, Tb927.7.1780 antibody, Arnit_0941 antibody, Saut_1231 antibody, Fbal_1180 antibody, PH_RS07970 antibody, PF_RS08760 antibody, PAB_RS02560 antibody, Aprt antibody, APRT antibody
    背景
    Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961
    Protein Interaction Partner: UBC, FN1, VCAM1, MLH1, ITGA4, NAPRT, HECW2, GMPS, UMPS, HPRT1, APP, IKBKG, APRT, VHL,
    Protein Size: 180
    分子量
    20 kDa
    基因ID
    353
    NCBI登录号
    NM_000485, NP_000476
    UniProt
    P07741
    途径
    Ribonucleoside Biosynthetic Process
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