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APRT 抗体 (N-Term)

The 兔 多克隆 anti-APRT antibody (ABIN2787672) specifically detects APRT in WB 和 IHC. The antibody is reactive with 人, 大鼠, 犬, Cow 和 豚鼠 samples.
产品编号 ABIN2787672
发货至: 中国
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Quick Overview for APRT 抗体 (N-Term) (ABIN2787672)

抗原

See all APRT 抗体
APRT (Adenine Phosphoribosyltransferase (APRT))

适用

人, 大鼠, 犬, Cow, 豚鼠

宿主

  • 47
  • 3

克隆类型

  • 49
  • 1
多克隆

标记

  • 29
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APRT antibody is un-conjugated

应用范围

  • 36
  • 19
  • 18
  • 10
  • 8
  • 7
  • 6
  • 4
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 14
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    N-Term

    序列

    ADSELQLVEQ RIRSFPDFPT PGVVFRDISP VLKDPASFRA AIGLLARHLK

    预测反应

    Cow: 79%, Dog: 79%, Guinea Pig: 86%, Human: 100%, Rat: 77%

    产品特性

    This is a rabbit polyclonal antibody against APRT. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human APRT
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 180 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    APRT (Adenine Phosphoribosyltransferase (APRT))

    别名

    APRT

    背景

    Adenine phosphoribosyltransferase (APRT) belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.Adenine phosphoribosyltransferase belongs to the purine/pyrimidine phosphoribosyltransferase family. A conserved feature of this gene is the distribution of CpG dinucleotides. This enzyme catalyzes the formation of AMP and inorganic pyrophosphate from adenine and 5-phosphoribosyl-1-pyrophosphate (PRPP). It also produces adenine as a by-product of the polyamine biosynthesis pathway. A homozygous deficiency in this enzyme causes 2,8-dihydroxyadenine urolithiasis. Two transcript variants encoding different isoforms have been found for this gene.
    Alias Symbols: AMP, DKFZp686D13177, MGC125856, MGC125857, MGC129961
    Protein Interaction Partner: UBC, FN1, VCAM1, MLH1, ITGA4, NAPRT, HECW2, GMPS, UMPS, HPRT1, APP, IKBKG, APRT, VHL,
    Protein Size: 180

    分子量

    20 kDa

    基因ID

    353

    NCBI登录号

    NM_000485, NP_000476

    UniProt

    P07741

    途径

    Ribonucleoside Biosynthetic Process
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