ACTR1A 抗体 (Middle Region)
Quick Overview for ACTR1A 抗体 (Middle Region) (ABIN2787670)
抗原
See all ACTR1A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- AIKERACYLS INPQKDETLE TEKAQYYLPD GSTIEIGPSR FRAPELLFRP
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against ACTR1A. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human ACTR1A
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 376 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ACTR1A (Alpha Centractin (ACTR1A))
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别名
- ACTR1A
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背景
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ACTR1A is a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin.This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60 % identical at the amino acid level to conventional actin. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ARP1, CTRN1
Protein Interaction Partner: HUWE1, SUMO2, UBC, NUP133, DCTN4, MYCBP, DCTN3, DCTN2, ACTR1B, LMNB1, COG3, ACTR10, SMURF1, RRS1, PSMD1, PSMC4, MYH9, MCM7, COPS5, CUL1, CUL3, SUMO1, Cep76, Actr1a, Dctn1, Capza1, HDAC6, SPTBN2, SPTBN1, NUMA1, BICD2,
Protein Size: 376 -
分子量
- 41 kDa
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基因ID
- 10121
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NCBI登录号
- NM_005736, NP_005727
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UniProt
- P61163
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途径
- M Phase
抗原
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