ACTN1 抗体 (N-Term)
Quick Overview for ACTN1 抗体 (N-Term) (ABIN2787669)
抗原
See all ACTN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- DHYDSQQTND YMQPEEDWDR DLLLDPAWEK QQRKTFTAWC NSHLRKAGTQ
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 75%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 85%
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产品特性
- This is a rabbit polyclonal antibody against ACTN1. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human ACTN1
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anti-Actinin, alpha 1 (ACTN1) (AA 1-330) antibody
ACTN1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 人, 小鼠, 猴 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 543-639) antibodyACTN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F1 unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 人 WB, IHC (p), IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) antibodyACTN1 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 28-260) antibodyACTN1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 1-204) antibodyACTN1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 1-892) antibodyACTN1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 1 (ACTN1) (AA 543-639) antibodyACTN1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 892 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ACTN1 (Actinin, alpha 1 (ACTN1))
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别名
- ACTN1
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背景
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Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ40884
Protein Interaction Partner: SPERT, KCTD6, MICALL2, MYOZ2, EPM2AIP1, OAS1, ACTN3, ACTN1, SUMO2, SUMO3, HSF5, UBC, MDM2, EZH2, BMI1, ACTN4, CDAN1, DCAF8, SF3A3, STAM2, SRP19, UBD, IGSF8, ICAM1, CD81, ERBB2IP, SVIL, PDHX, RPS27, PSMA1, KPNA2, HCVgp1, PIAS4, GIT2, NUMBL, HSP90AB1, HSP90
Protein Size: 892 -
分子量
- 103 kDa
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基因ID
- 87
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NCBI登录号
- NM_001102, NP_001093
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UniProt
- P12814
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途径
- Cell-Cell Junction Organization
抗原
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