H2AFY 抗体 (N-Term)
Quick Overview for H2AFY 抗体 (N-Term) (ABIN2787623)
抗原
See all H2AFY 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- HPKYRIGVGA PVYMAAVLEY LTAEILELAG NAARDNKKGR VTPRHILLAV
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 93%, Zebrafish: 100%
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产品特性
- This is a rabbit polyclonal antibody against H2AFY. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human H2AFY
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anti-H2A Histone Family, Member Y (H2AFY) (AA 109-369) antibody
H2AFY 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (AA 123-372) antibodyH2AFY 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (AA 123-372) antibodyH2AFY 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) antibodyH2AFY 适用: 人, 大鼠, 小鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (AA 144-193) antibodyH2AFY 适用: 人, 大鼠, 小鼠, Cow, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (N-Term) antibodyH2AFY 适用: 人, 大鼠, 小鼠, Cow, 马, 犬, 豚鼠, 兔, Pig, 猴, Bat, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (AA 36-85) antibodyH2AFY 适用: 人, 大鼠, 小鼠, Cow, 马, 犬, 豚鼠, 兔, Pig, 猴, 斑马鱼, Bat, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (Middle Region) antibodyH2AFY 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-H2A Histone Family, Member Y (H2AFY) (N-Term) antibodyH2AFY 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 371 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- H2AFY (H2A Histone Family, Member Y (H2AFY))
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别名
- H2AFY
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背景
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. H2AFY is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: H2A.y, H2A/y, H2AF12M, H2AFJ, MACROH2A1.1, mH2A1, macroH2A1.2
Protein Interaction Partner: ERICH2, UBC, SUMO2, SUMO3, HIST1H3A, H3F3A, SUZ12, EED, RNF2, EZH2, BMI1, SRPK1, LMNA, ATF2, FN1, HIST1H3B, CENPA, APP, CBX5, CBX3, DIDO1, UBD, ATXN1L, NEDD8, ERBB2, SUMO1, HDGF, HDAC2, HDAC1, PARP1, tat, CUL3, SPOP, WDR77, PHF14, DEK, XRCC5, TOP1, RAN, H
Protein Size: 371 -
分子量
- 39 kDa
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基因ID
- 9555
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NCBI登录号
- NM_001040158, NP_001035248
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UniProt
- O75367
抗原
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