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HMGB2 抗体 (Middle Region)

The 兔 多克隆 anti-HMGB2 antibody is suitable to detect HMGB2 in samples from 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼 和 Pig. It has been validated for WB 和 IHC.
产品编号 ABIN2787574
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for HMGB2 抗体 (Middle Region) (ABIN2787574)

抗原

See all HMGB2 抗体
HMGB2 (High Mobility Group Box 2 (HMGB2))

适用

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人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 豚鼠, 斑马鱼, Pig

宿主

  • 70
  • 11
兔

克隆类型

  • 47
  • 34
多克隆

标记

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This HMGB2 antibody is un-conjugated

应用范围

  • 59
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  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    • 5
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    Middle Region

    原理

    HMGB2 Antibody - middle region

    序列

    DREMKNYVPP KGDKKGKKKD PNAPKRPPSA FFLFCSEHRP KIKSEHPGLS

    预测反应

    Cow: 100%, Dog: 100%, Guinea Pig: 87%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 80%

    产品特性

    This is a rabbit polyclonal antibody against HMGB2. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human HMGB2
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58157-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    HMGB2 (High Mobility Group Box 2 (HMGB2))

    别名

    HMGB2

    背景

    Background Information: HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. HMGB2 was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

    Gene Name: High mobility group box 2

    Alternative Symbols: HMG2

    Protein Name: High mobility group protein B2

    分子量

    24kDa

    基因ID

    3148

    NCBI登录号

    NP_002120

    UniProt

    P26583

    途径

    Cellular Response to Molecule of Bacterial Origin
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