MED14 抗体 (Middle Region)
Quick Overview for MED14 抗体 (Middle Region) (ABIN2787568)
抗原
See all MED14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- AADREDSPAM ALLLQQFKEN IQDLVFRTKT GKQTRTNAKR KLSDDPCPVE
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预测反应
- Human: 100%, Mouse: 79%, Rabbit: 86%
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产品特性
- This is a rabbit polyclonal antibody against MED14. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human MED14
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anti-Mediator Complex Subunit 14 (MED14) (Internal Region) antibody
MED14 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 14 (MED14) (AA 586-615) antibodyMED14 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB20179 unconjugated
anti-Mediator Complex Subunit 14 (MED14) antibodyMED14 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 14 (MED14) (AA 575-624) antibodyMED14 适用: 人, 小鼠, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Mediator Complex Subunit 14 (MED14) (AA 701-750) antibodyMED14 适用: 人, 小鼠 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1454 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- MED14 (Mediator Complex Subunit 14 (MED14))
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别名
- MED14
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背景
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The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation.
Alias Symbols: CRSP150, CRSP2, CSRP, CXorf4, DRIP150, EXLM1, MGC104513, RGR1, TRAP170
Protein Interaction Partner: UBC, HECW2, CDK8, CDK19, MED12, ESR1, MED19, MED26, PPARG, FBXW7, EPAS1, MED11, MED8, MED29, MED18, MED4, PPP6R1, MED16, MED13, MED24, MED27, MED17, MED21, MED1, CTDP1, SREBF1, DCTN1, ACTN2, ACTN1, MED10, UACA, NECAB2, MED25, MED15, CRSP5, MED7, MED23, VD
Protein Size: 1454 -
分子量
- 160 kDa
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基因ID
- 9282
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NCBI登录号
- NM_004229, NP_004220
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UniProt
- O60244
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
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